POSTPONED
12:00-12:30 Flash talks (5x5min)
12:30-13:30 Lunch and poster session
Tau therapeutic strategies
13:30-13:50 Isabelle Landrieu (Univ. Lille, France)
Heavy-chain-only antibodies: new tools for studying tau structure
13:50-14:10 Norbert Zilka (Axon Neuroscience)
Immunotherapy targeting extracellular tau: microglia in the spotlight
14:10-14:25 Claude Wischik (TauRx Pharmaceuticals) What we have learned from the first tau-based Phase 3 trials in mild-moderate AD?
14:25-14:40 Isabel Lastres-Becker (Madrid, Spain)
Cannabinoid receptor CB2 deficiency protects against tau-induced neurodegeneration
14:40-14:55 Selected from abstract
14:55-15:15 Yijuang Chern (Academia Sinica, Taipei, Taiwan)
Adenosine modulators and Alzheimer pathology
15:15-15:35 Malika Hamdane (Univ. Lille, France)
Targeting amino-truncated tau species
15:35 Prizes Flash talks and posters
16:00 Round table - Concluding remarks
Understanding tau aggregation
8:30-8:50 Jean-Pierre Brion (ULB, Brussels, Belgium)
Title to come
8:50-9:10 Diane Hanger (KCL, London, UK)
Tau cleavage and tau phosphorylation in human tauopathy
9:10-9:30 Amrit Mudher (Univ. Southampton, UK)
Biophysical and biochemical characterisation of aggregating tau species as they evolve in vivo in two transgenic models of tauopathy
9:30-9:50 Miguel Medina (Ciberned, Spain)
The role of Tyr phosphorylation on tau secretion
9:50-10:10 Ioannis Sotiropoulos (Univ. Minho, Braga)
Lifetime stress as a precipitator of pathological brain aging & dementia: the focus on tau
10:10-10-45 Coffee break and poster session
Selected from abstracts
10:45-11:00 Wendy Noble (KCL, UK) Bin1 protein loss in AD promotes synaptictau accumulation and disrupts tau release
11:00-11:15 Yann Fichou (Santa Barbara, CA) Tau inter-twins with co-factors: how it modulates complex phase separations, oligomerization and aggregation properties.
11:15-11:30 Simon Dujardin (MGH Harvard Univ, MA) Tau molecular diversity mediates clinical heterogeneity in AD
11:30-11:45 Lukasz Joachimiak (Dallas, TX) Conforma-tional insights into tau aggregation
11:45-12:00 François Devred (Univ Aix Marseille) Role of zinc in tau aggregation
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Alzheimer & Tauopathies - Luc Buée
Copyright 2020